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Priya, Srinivas and Pillai, M R (2020) Therapeutic application of nitric oxide in cancer & inflammatory disorders. The Indian journal of medical research, 151 (4). pp. 383-385. ISSN 0971-5916

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Abstract

The present book discusses the therapeutic applications of nitric oxide (NO) in three parts; the first in cancers, the second in inflammatory diseases and the third part involves the collection of abstracts from the conference held in Siena, Italy, on October 4-5, 2018. This book is designed to share knowledge from the highly reputed eminent researchers and clinicians in the field of NO and related bioactive nitrogen oxides, as signalling molecules in physiological and pathophysiological states. In the first chapter, the role of NO donor nanoparticles to be used for cancer chemotherapy is discussed as it would release NO at target site, contributing to the reversal of multidrug resistance (MDR) in cancer cells, in comparison with lower doses, which given independently does not have the potential to trigger apoptosis. This nanoparticle which has the ability to induce leakiness in the blood vessels, when combined with traditional cancer chemotherapeutic agents, has been discussed to provide effective treatment outcomes.

Item Type: Article
Subjects: Cancer Research
Depositing User: Central Library RGCB
Date Deposited: 08 Apr 2021 09:27
Last Modified: 08 Apr 2021 09:27
URI: http://rgcb.sciencecentral.in/id/eprint/1033

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