PM, Sheeba and E, Sreekumar (2014) A Comparative Study of Dengue Syndromes in a Tertiary Care Centre. Academic Medical Journal of India, 11(2). ISSN 2347 – 5919

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Abstract

Cyclic dengue epidemics have been reported from Kerala state since 2001. The DEN-1 and DEN-4 viruses had been detected since 1970s from the human sera in a few districts of Kerala. Circulation of multiple serotypes is associated with complications of dengue, namely Dengue Haemorrhagic Fever (DHF) / Dengue Shock Syndrome (DSS). A descriptive study was done from 16th August 2008 to 15th August 2009 in which clinical and laboratory parameters of dengue were documented. From the study group, blood samples were collected and IgG and IgM dengue antibodies were detected in the serum. Serotyping was done at Rajiv Gandhi Centre of Biotechnology by PCR. Dengue Fever (DF) without complications was seen in 94.03% primary and 68.42% secondary cases and DHF/DSS was seen in 5.9% of primary and 31.57% of secondary cases. Fever, headache, body-ache and myalgia were the common symptoms at presentation. Commonest bleeding manifestations were purpura and petechiae. Malena was more often associated with DHF/DSS. Facial puffiness was seen associated with DHF/DSS in the lower age groups. Retro-orbital pain was equally observed in DF and DHF/DSS. DHF/DSS was observed in increased proportion in children; 36% of children had DHF/DSS, where as it was only 10% in the case of adults. Vomiting and abdominal pain were predominant in DHF/DSS group. Hepatomegaly was more in the DHF/DSS group. A positive tourniquet test showed greater association with DHF/DSS. Elevated liver enzymes and hypoproteinemia was observed in DHF/DSS with greater significance. Serotype isolated in this outbreak was Dengue serotype 1.

Item Type:	Article
Uncontrolled Keywords:	Dengue, Dengue Fever, Dengue Haemorrhagic Fever, Dengue Shock Syndrome
Subjects:	Viral Disease Biology
Depositing User:	Central Library RGCB
Date Deposited:	06 Jan 2017 04:06
Last Modified:	06 Jan 2017 04:06
URI:	http://rgcb.sciencecentral.in/id/eprint/118

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