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Eun , Jin Kim and Chan, Hee Lee and G, Balakrish Nair and Dong, Wook Kim (2015) Whole-genome sequence comparisons reveal the evolution of Vibrio cholerae O1. Trends in Microbiology, 23. pp. 479-489. ISSN 0966-842X

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Abstract

Highlights • Recombination between phages CTX and RS1, and point mutations in the cholera toxin gene ctxB, generate new CTXs. • Population shift in Vibrio cholerae is accompanied by a change in CTX, particularly in the gene ctxB. • V. cholerae uses a genetic mechanism to replace an old CTX with a new CTX. • Population shifts in V. cholerae might be caused by changes in existing immunity. • Understanding the selection of a particular strain will help us to combat cholera.

Item Type: Article
Uncontrolled Keywords: Vibrio cholerae; cholera; cholera toxin; phage CTX
Subjects: Microbiome Research
Depositing User: Rgcb Library
Date Deposited: 23 Dec 2016 05:30
Last Modified: 27 Dec 2016 06:36
URI: http://rgcb.sciencecentral.in/id/eprint/56

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