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Revathy, Nadhan and SatheeshKumar, Sengodan and SreelathaKrishnakumar , Hemalatha and Arathi, Rajan and Geetu Rose, Varghese and Neetha, RL and Amritha Krishna, BV and Ratheeshkumar, Thankappan and Priya, Srinivas (2017) Insights into dovetailing GTD and Cancers. Critical reviews in oncology/hematology, 114. 77-90. ISSN 1879-0461

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Gestational trophoblastic diseases (GTD) encompass a group of placental tumors which mostly arise due to certain fertilization defects, resulting in the over-proliferation of trophoblasts. The major characteristic of this diseased state is that β-hCG rises up manifold than that is observed during pregnancy. The incidence of GTD when analyzed on a global scale, figures out that there is a greater risk in South-East Asia, the reason of which remains unclear. An insight into any possible correlation of GTD incidence with cancers, other than choriocarcinoma, is being attempted here. Also, we review the recent developments in research on the molecular etiopathology of GTD. This review would render a wider eye towards a new paradigm of thoughts to connect GTD and breast cancer, which has not been into the picture till date.

Item Type: Article
Uncontrolled Keywords: GTD Cancers Trophoblast β-hCG Breast cancer
Subjects: Cancer Research
Depositing User: Central Library RGCB
Date Deposited: 23 May 2018 07:45
Last Modified: 23 May 2018 07:46
URI: http://rgcb.sciencecentral.in/id/eprint/593

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