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Vineethkumar, T V and Shyla, G and Sanil , George (2018) SMALLEST LECTIN-LIKE PEPTIDE IDENTIFIED FROM THE SKIN SECRETION OF AN ENDEMIC FROG, HYDROPHYLAX BAHUVISTARA. Acta biologica Hungarica, 69 (1). pp. 110-113. ISSN 0236-5383

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Abstract

Lectins are sugar-binding proteins and considered as attractive candidates for drug delivery and targeting. Here, we report the identification of the smallest lectin-like peptide (odorranalectin HYba) from the skin secretion of Hydrophylax bahuvistara which is being the shortest lectin-like peptide identified so far from the frog skin secretion, with 15 amino acid residues. The peptide is the first report from an Indian frog and lacks antimicrobial activity but strongly agglutinate intact human erythrocytes. The sequences at the L-fucose recognizing region is conserved as in other lectins reported from frog skin secretion and could be exploited for specificity and drug targeting properties.

Item Type: Article
Uncontrolled Keywords: Agglutination; Hydrophylax; amphibian; antimicrobial; lectin
Subjects: Chemical Biology
Depositing User: Rgcb Library
Date Deposited: 27 Jul 2018 06:03
Last Modified: 11 Apr 2019 11:14
URI: http://rgcb.sciencecentral.in/id/eprint/666

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