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Jayesh , Antony and Minakshi , Saikia and Ruby , John Anto (2015) Phytochemicals from Fruits and Vegetables as potential anti-cancer agents: special reference to skin cancer. In: Anticancer properties of fruits and vegetables: A scientific review. Anticancer properties of fruits and vegetables. pp. 277-307. ISSN ISBN: 978-981-4508-88-9

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The risk of development of chronic diseases including cancer is reported to have significantly reduced when there is a high dietary intake of functional foods that contain significant amounts of bioactive components. Skin cancer is the most common type of cancer in white people around the world and among the different type of skin cancers, malignant melanoma has a much higher mortality rate. In this scenario, fruits and vegetables may provide desirable health benefits beyond basic nutrition, since they contain several active principles which contribute to their vivid biological functions, including the chemopreventive and chemotherapeutic properties. Even though numerous in vitro and in vivo studies have been reported on the anticancer potential of these compounds, only very few clinical trials have been conducted and a few more are ongoing, to assess their therapeutic efficacy. Since the preliminary results obtained from in vitro and in vivo studies appear to be promising, more future investigations and clinical trials with systematic follow up are warranted in this area. In this context, we have conducted a detailed review of various compounds derived from fruits and vegetables, which negatively regulate the development of skin cancer. We have also performed a detailed analysis of various target molecules, regulated by these compounds in the multiple signaling pathways leading to skin carcinogenesis.

Item Type: Article
Subjects: Cancer Research
Depositing User: Rgcb Library
Date Deposited: 30 Apr 2019 09:24
Last Modified: 30 Apr 2019 09:24
URI: http://rgcb.sciencecentral.in/id/eprint/738

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