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Viji , Remadevi and Lakshmi , Mohan Lathika and Anjana , Sasikumar Sujatha and Sreeja , Sreeharshan (2019) Ficus extract—A promising agent for antimammary tumorigenesis: A review on current status and future possibilities. Phytotherapy research , 33 (6). pp. 1597-1603. ISSN 1099-1573

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Pharmacological studies have shown that various species of Ficus have antiviral, antidiarrheal, antipyretic, hypolipidemic, antidiabetic, antioxidant, anticancer, antiparasitic, antiangiogenic, anti‐inflammatory, antibacterial, antiplatelet, reproductive, dermatological, immunological, endocrine, and hepato and nephron protective effects. But there is no sufficient research on biomolecules present in the leaf extract of Ficus religiosa and its mechanism of action. We have previously reported that bioavailable constituents of F. religiosa leaf extract exert photosensitizing and apoptosis‐inducing capability through the generation of intracellular reactive oxygen species on breast cancer cells. In this review, we have evaluated the expression of checkpoint proteins of G1/S and sub G0 phase with wet lab data and also have done a data mining of other research for other potential mechanistic action of the F. religiosa leaf extract.

Item Type: Article
Uncontrolled Keywords: Ficus religiosa; breast cancer; chemo sensitizer; photosensitizing effect
Subjects: Cancer Research
Depositing User: Central Library RGCB
Date Deposited: 15 Jul 2019 10:12
Last Modified: 15 Jul 2019 10:12
URI: http://rgcb.sciencecentral.in/id/eprint/825

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