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Anil , Kumar and Vibin, Ramakrishnan (2010) Creating novel protein scripts beyond natural alphabets. Systems and synthetic biology, 4 (4). 247-256 . ISSN 1872-5333

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Natural proteins are concatenated amino acids with definite handedness or chirality, with their spatial orientation being preferentially left handed or L-chiral. This paper discusses the biophysics of stereo-chemical perturbation to proteins using D-(α) amino acid and its utility as an additional design alphabet while scripting novel protein structures.

Item Type: Article
Uncontrolled Keywords: Heterochiral proteins; Polypeptide stereochemistry; Protein design; Protein structure energetics
Subjects: Chemical Biology
Depositing User: Rgcb Library
Date Deposited: 30 Aug 2019 09:28
Last Modified: 30 Aug 2019 09:28
URI: http://rgcb.sciencecentral.in/id/eprint/855

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