Sweda, Sreekumar and E. V., Soniya (2017) Artificial MicroRNAs Promote High-Level Production of Biomolecules Through Metabolic Engineering of Phenylpropanoid Pathway. CRITICAL REVIEWS IN PLANT SCIENCES, 36. pp. 353-366. ISSN 0735-2689

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Abstract

Plant microRNAs (miRNAs) are tiny RNAs that are crucial for the biosynthesis of secondary metabolites such as phenylpropanoids because they regulate the activity of key transcription factors and enzymes. Here, we have discussed the significance of miRNAs that target the mRNAs encoding for enzymes and transcription factors in the phenylpropanoid pathway. Genes encoding the miRNAs involved in the synthesis of phenylpropanoids could be considered as potential candidates for metabolic engineering. We have analyzed the construction and potential value of artificial miRNAs (amiRNAs) that could be used for scrutinizing the functional importance of miRNAs in phenylpropanoid biosynthesis and manipulating the pathway for enhancing the production of secondary metabolites.

Item Type:	Article
Uncontrolled Keywords:	Flavonoid; lignin; noncoding; secondary metabolite; silencing; transcription factor
Subjects:	Plant Disease Biology & Biotechnology
Depositing User:	Central Library RGCB
Date Deposited:	06 May 2019 10:11
Last Modified:	06 May 2019 10:11
URI:	http://rgcb.sciencecentral.in/id/eprint/744

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