Krithiga, Kuppusamy and Aarathi , Rajan and Aarathy , Warrier and Revathy , Nadhan and Dipyaman, Patra and Priya , Srinivas (2019) Cytological Grading of Breast Tumors—The Human and Canine Perspective. Frontiers in veterinary science, 6 (283). ISSN 2297-1769

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Abstract

Human breast cancers (HBCs) are one of the leading causes of global cancer death among women. Domesticated canines are the most affected domestic species with a prevalence rate of breast cancer more than three times in women. While the human cancer patients receive substantial diagnostic and treatment facilities, inadequacy in canine cancer care, calls for greater attention. Fine Needle Aspiration Cytology (FNAC) is comparatively simple, quick, and easily reproducible technique, which aids in pre-surgical diagnosis. In humans, FNAC has a standard protocol, the Robinson's grading system, which has high correlation with the established histological grading system of Scarff Bloom- Richardson. However, Canine Mammary Tumors (CMTs), which are known to be similar to HBCs in biological behavior and gene expressions, still bank on the histopathological methods for diagnostic purposes. This review sheds light on various factors that could be considered for developing a standard FNAC technique for CMT grading and analyzes its future perspectives.

Item Type:	Article
Uncontrolled Keywords:	breast, canine, cytology, grading, human, tumor
Subjects:	Cancer Research
Depositing User:	Central Library RGCB
Date Deposited:	27 Jan 2020 10:03
Last Modified:	27 Jan 2020 10:03
URI:	http://rgcb.sciencecentral.in/id/eprint/937

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